Accès direct au contenu


Bienvenue dans l'UMR Inserm U930



Publications Majeures

Inhibition of Pathogenic Mutant SOD1 Aggregation in Cultured Motor Neuronal Cells by Prevention of Its SUMOylation on Lysine 75.

Neurodegener Dis. 2016;16(3-4):161-71. doi: 10.1159/000439254.
 

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology.

J Proteome Res. 2015 Dec 4;14(12):5273-82. doi: 10.1021/acs.jproteome.5b00699.
 

Impact of Sonothrombolysis on in vitro Blood Clot: Pictographic Validation with Electron Microscopy.

Ultraschall Med. 2015 Sep 2. [Epub ahead of print] No abstract available.
 

GABA/Glutamate synaptic pathways targeted by integrative genomic and electrophysiological explorations distinguish autism from intellectual disability.

Mol Psychiatry. 2016 Mar;21(3):411-8. doi: 10.1038/mp.2015.75.
 

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study.

Neurobiol Aging. 2015 Apr;36(4):1639-52. doi: 10.1016/j.neurobiolaging.2014.11.023.
 

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.

Int J Neuropsychopharmacol. 2014 Oct 31;18(4). pii: pyu044. doi: 10.1093/ijnp/pyu044.
 

FIBRASCAN: a novel method for 3D white matter tract reconstruction in MR space from cadaveric dissection.

Neuroimage. 2014 Dec;103:106-18. doi: 10.1016/j.neuroimage.2014.09.016.
 

Variational segmentation of vector-valued images with gradient vector flow.

IEEE Trans Image Process. 2014 Nov;23(11):4773-85. doi: 10.1109/TIP.2014.2353854.
 

Axial ultrasound B-scans of the entire eye with a 20-MHz linear array: correction of crystalline lens phase aberration by applying Fermat's principle.

IEEE Trans Med Imaging. 2014 Nov;33(11):2149-66. doi: 10.1109/TMI.2014.2332519.
 

Ultrasound measurements of brain tissue pulsatility correlate with the volume of MRI white-matter hyperintensity.

J Cereb Blood Flow Metab. 2014 Jun;34(6):942-4. doi: 10.1038/jcbfm.2014.58.
 

Untargeted 1H-NMR metabolomics in CSF: toward a diagnostic biomarker for motor neuron disease.

Neurology. 2014 Apr 1;82(13):1167-74. doi: 10.1212/WNL.0000000000000274.
 

Early visual ERPs are influenced by individual emotional skills.

Soc Cogn Affect Neurosci. 2014 Aug;9(8):1089-98. doi: 10.1093/scan/nst084.
 

Irinotecan delivery by microbubble-assisted ultrasound: in vitro validation and a pilot preclinical study.

Mol Pharm. 2013 Jul 1;10(7):2667-75. doi: 10.1021/mp400081b.
 

A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS.

Hum Mutat. 2013 Jul;34(7):953-60. doi: 10.1002/humu.22329.
 

Brain correlates of automatic visual change detection.

Neuroimage. 2013 Jul 15;75:117-22. doi: 10.1016/j.neuroimage.2013.02.050.
 

Resting-state cerebral blood flow in amygdala is modulated by sex and serotonin transporter genotype.

Neuroimage. 2013 Aug 1;76:90-7. doi: 10.1016/j.neuroimage.2013.03.003.
 

Molecular imaging of microglial activation in amyotrophic lateral sclerosis.

PLoS One. 2012;7(12):e52941. doi: 10.1371/journal.pone.0052941.
 

The neurobiology of depression and antidepressant action.

Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 1):2331-71. doi: 10.1016/j.neubiorev.2012.12.007. Review.
 

Neurogenesis-independent antidepressant-like effects on behavior and stress axis response of a dual orexin receptor antagonist in a rodent model of depression.

Neuropsychopharmacology. 2012 Sep;37(10):2210-21. doi: 10.1038/npp.2012.70.
 

Quality of life of adolescents with autism spectrum disorders: comparison to adolescents with diabetes.

Eur Child Adolesc Psychiatry. 2012 May;21(5):289-96. doi: 10.1007/s00787-012-0263-z.
 

Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment.

Eur J Nucl Med Mol Imaging. 2012 Apr;39(4):621-31. doi: 10.1007/s00259-011-2021-8.
 

Genetic modulation of neural response during working memory in healthy individuals: interaction of glucocorticoid receptor and dopaminergic genes.

Mol Psychiatry. 2013 Feb;18(2):174-82. doi: 10.1038/mp.2011.145.
 

Can pupil size and pupil responses during visual scanning contribute to the diagnosis of autism spectrum disorder in children?

J Psychiatr Res. 2011 Aug;45(8):1077-82. doi: 10.1016/j.jpsychires.2011.01.008.
 

Antidepressants recruit new neurons to improve stress response regulation.

Mol Psychiatry. 2011 Dec;16(12):1177-88. doi: 10.1038/mp.2011.48.
 


Notre Mission:
L’unité Mixte de Recherche “Imagerie et Cerveau” Inserm UMR930, Université François Rabelais de Tours s’intéresse au développement cérébral normal et pathologique, de la période périnatale à l’âge adulte. Son principal objectif est la mise en place, la validation et l’utilisation en recherche clinique de méthodes d’imagerie (IRM, TEP, SPECT, EEG, ultrasons) afin d’aider à la compréhension des mécanismes physiopathologiques impliqués dans le développement et le fonctionnement du cerveau.

 


   

Contactez nous

CHRU de Tours - Hôpital Bretonneau
2 boulevard Tonnellé
Bâtiment B1A, 1er étage
37044 Tours Cedex 9 France  
Secrétariat de l'unité
Tel : + 33 (0)2 47 36 63 51
Email : u930@univ-tours.fr


Consultez l'actualité de l'Université
Retour au site institutionnel